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Filtered Search Results
Medchemexpress LLC VARI FLUOR 555 CARBO 1 mg
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VARI FLUOR 555 CARBO 1MG
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Medchemexpress LLC VARI FLUOR 488 CARBO 5 mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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VARI FLUOR 488 CARBO 5MG
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Apexbio Technology LLC NVP-BHG712 940310-85-0 200mg
NVP-BHG712 (CAS 940310-85-0) is a selective small molecule inhibitor targeting the EphB4 receptor tyrosine kinase exhibiting an ED50 of 5 nM for EphB4 and reduced activity toward VEGFR2 (ED50 4200 nM) NVP-BHG712 demonstrates potent inhibition of EphB4 phosphorylation in cellular assays and shows weaker effects on EphB2 EphA2 EphB3 and EphA3 In cell-based models NVP-BHG712 suppresses proliferation and viability of synovial sarcoma cells and increases paclitaxel sensitivity in HEK293/ABCC10 cells In vivo it inhibits VEGF-induced angiogenesis and reduces tumor growth and metastasis in murine xenograft models This compound is a valuable probe for studying EphB4-mediated signaling in cancer and angiogenesis research
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Apexbio Technology LLC NP118809 41332-24-5 200mg
NP118809 (CAS 41332-24-5) is a potent and selective blocker of N-type voltage-gated calcium channels exhibiting an IC50 of 0 11 M in vitro It demonstrates significant selectivity over L-type calcium channels with over 100-fold preference (L-type IC50 12 2 M) In vivo studies in rats indicate that NP118809 is orally bioavailable (mean 30%) with a Tmax of 2 3 hours and a half-life of 2 1 hours following intravenous or oral administration The compound exhibits wide tissue distribution and has been shown to produce analgesic effects in animal pain models NP118809 is useful for research into N-type calcium channel function and modulation particularly in studies of pain signaling and neuropharmacology
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Apexbio Technology LLC CYT387 1056634-68-4 200mg
CYT387 (CAS 1056634-68-4) is an aminopyrimidine derivative identified through high-throughput screening and optimized with structure-guided medicinal chemistry It functions as an inhibitor targeting Janus kinase family enzymes JAK1 JAK2 JAK3 and TYK2 with reported IC50 values of 11 nM 18 nM 155 nM and 17 nM respectively At concentrations between 500 1500 nM CYT387 selectively suppresses JAK2 signaling inhibits proliferation of JAK2-dependent hematopoietic cell lines and induces apoptosis with minimal effects on non-hematopoietic cells CYT387 is employed in experimental studies of JAK2-mediated signaling pathways and myeloproliferative neoplasms
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Apexbio Technology LLC Vemurafenib (PLX4032, RG7204) 918504-65-1 200mg
Vemurafenib (PLX4032 RG7204 CAS 918504-65-1) is a small-molecule inhibitor targeting BRAF kinase primarily inhibiting the activity of the oncogenic BRAF V600E mutant by competitively binding its ATP-binding site It also inhibits related kinases such as CRAF ARAF and wild-type BRAF In cells lacking BRAF mutations vemurafenib may paradoxically stimulate downstream MEK signalling due to transactivation mechanisms within RAF dimers Vemurafenib serves as an important research tool for investigating RAF-mediated signaling pathways in oncology particularly in melanoma studies
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Aobchem 3-Bromo-7-nitroquinoline | ≥97% | CAS 1354221-07-0 | C9H5BrN2O2 | 500mg
3-Bromo-7-nitroquinoline | ≥97% | CAS 1354221-07-0 | C9H5BrN2O2 | 500mg
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Aobchem 3-Bromo-7-nitroquinoline | ≥97% | CAS 1354221-07-0 | C9H5BrN2O2 | 1g
3-Bromo-7-nitroquinoline | ≥97% | CAS 1354221-07-0 | C9H5BrN2O2 | 1g
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Aobchem 3-Bromo-7-nitroquinoline | ≥97% | CAS 1354221-07-0 | C9H5BrN2O2 | 5g
3-Bromo-7-nitroquinoline | ≥97% | CAS 1354221-07-0 | C9H5BrN2O2 | 5g
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![eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Ambeed | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 100g | 491642014](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471436.jpg-250.jpg)
eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Ambeed | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 100g | 491642014
4-Chloro-3-nitroquinoline | Ambeed | 39061-97-7 | MFCD07369246 | 208.600 | C9H5ClN2O2 | 97.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 100g | 491642014
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Ambeed AMBEED
5000847190 7-NITROQUINOLINE 500G
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![eMolecules 56-57-5 | 4-Nitroquinoline n-oxide | Combi-Blocks | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 5g | 335368515](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492416.jpg-250.jpg)
eMolecules 56-57-5 | 4-Nitroquinoline n-oxide | Combi-Blocks | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 5g | 335368515
4-Nitroquinoline n-oxide | Combi-Blocks | 56-57-5 | MFCD00006738 | 190.158 | C9H6N2O3 | 98.000 | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 | 5g | 335368515
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![eMolecules 17576-53-3 | 3-Nitroquinoline | ChemScene | MFCD00956379 | 174.159 | C9H6N2O2 | 98.000 | [O-][N+](=O)c1cnc2ccccc2c1 | 250mg | 632323140](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502483472.JPG-250.jpg)
eMolecules 17576-53-3 | 3-Nitroquinoline | ChemScene | MFCD00956379 | 174.159 | C9H6N2O2 | 98.000 | [O-][N+](=O)c1cnc2ccccc2c1 | 250mg | 632323140
3-Nitroquinoline | ChemScene | 17576-53-3 | MFCD00956379 | 174.159 | C9H6N2O2 | 98.000 | [O-][N+](=O)c1cnc2ccccc2c1 | 250mg | 632323140
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![eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Synthonix | MFCD07369246 | 208.600 | C9H5ClN2O2 | 95.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 25g | 831794068](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000491361.jpg-250.jpg)
eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Synthonix | MFCD07369246 | 208.600 | C9H5ClN2O2 | 95.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 25g | 831794068
4-Chloro-3-nitroquinoline | Synthonix | 39061-97-7 | MFCD07369246 | 208.600 | C9H5ClN2O2 | 95.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 25g | 831794068
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![eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Synthonix - Stock | MFCD07369246 | 208.600 | C9H5ClN2O2 | 95.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 10g | 452564970](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492802.jpg-250.jpg)
eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Synthonix - Stock | MFCD07369246 | 208.600 | C9H5ClN2O2 | 95.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 10g | 452564970
4-Chloro-3-nitroquinoline | Synthonix - Stock | 39061-97-7 | MFCD07369246 | 208.600 | C9H5ClN2O2 | 95.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 10g | 452564970
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